Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production

Double-stranded DNA (dsDNA) in the cytoplasm triggers the production of interleukin 1β (IL-1β) as an antiviral host response, and deregulation of the...
Full description

Saved in:
PPN (Catalogue ID):

NLM237709880

Persons:

Roth, Susanne

Rottach, Andrea

Lotz-Havla, Amelie S

Laux, Verena

Muschaweckh, Andreas

Gersting, Søren W

Muntau, Ania C

Hopfner, Karl-Peter

Jin, Lei

Vanness, Katelynd

Petrini, John H J

Drexler, Ingo

Leonhardt, Heinrich

Ruland, Jürgen

Media type:

Electronic Article

Formangabe:

Adaptor Proteins, Signal Transducing

B-Cell CLL-Lymphoma 10 Protein

Bcl10 protein, mouse

CARD Signaling Adaptor Proteins

CARD9 protein, human

DNA, Viral

DNA-Binding Proteins

Interleukin-1beta

Membrane Proteins

NF-kappa B

Sting1 protein, mouse

Tlr4 protein, mouse

Tlr9 protein, mouse

Toll-Like Receptor 4

Toll-Like Receptor 9

Acid Anhydride Hydrolases

EC 3.6.-

Rad50 protein, human

DNA Repair Enzymes

EC 6.5.1.-

Extent:

Online-Ressource

Language:

English

Keywords:

Journal Article / Research Support, N.I.H., Extramural

Adaptor Proteins, Signal Transducing / B-Cell CLL-Lymphoma 10 Protein / Bcl10 protein, mouse / CARD Signaling Adaptor Proteins / CARD9 protein, human / DNA, Viral / DNA-Binding Proteins / Interleukin-1beta / Membrane Proteins / NF-kappa B

Sting1 protein, mouse

Tlr4 protein, mouse

Tlr9 protein, mouse

Toll-Like Receptor 4

Toll-Like Receptor 9

Acid Anhydride Hydrolases

EC 3.6.-

Rad50 protein, human

DNA Repair Enzymes

EC 6.5.1.-

Further Keywords:

Journal Article

Research Support, N.I.H., Extramural

General Note:

Date Completed 28.07.2014

Date Revised 08.01.2021

published: Print-Electronic

CommentIn: Nat Immunol. 2014 Jun;15(6):534-6. - PMID 24840992

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Containing Work:

in: Nature immunology - Vol. 15, No. 6 (2014), p. 538-45

DOI/URN:

10.1038/ni.2888

Order/plate number:

pubmed21n1095.xml

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